MOLECULAR EPIDEMIOLOGY OF ANTIBIOTIC RESISTANT GENES IN PATHOGENIC BACTERIA, (A CASE STUDY OF KHYBER PUKIITUNKIIWA, PAKISTAI9

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dc.contributor.authorJohar Jamil
dc.contributor.authorSupervised By: Prof. Dr. Bashir Ahmad
dc.date.accessioned2026-07-17T03:29:06Z
dc.date.available2026-07-17T03:29:06Z
dc.date.issued2013
dc.description.abstractThis study was conducted from 2009 to 2012 on isolates collected from two tedary hospitals of Peshawar, I(iyber Pakhtunkhwa, Pakistan. The aim ofthis study was to find out the resistance profile of different antibiotics and biocides, prevalence of extendedspectum flactamases (ESBLs) and caxbapenemases ilt ,t aureus, E. coli, Klebsiella spp_ eJtd P. aeruginosa, rcspectively. Among 133 S. aureus, 4'7yo werc Methicillin resistant S azreus (MRSA). Cefoxitin was found to be the most efficient and effective method for the detection of MRSA. In S. aureus, 'tal]lcomycir' (VAN) and linzolid (LZD) showed best activity against both MRSA and MSSA. High level of antibiotic resista[ce was found in MRSA isolates. Most of our ,S. arrem isolates were susceptible to biocides. The genes including sea and pvl were the most dominant genes in S. a,rezs isolates. Carbapenems including meropenem and imipenem showed very good activity against E coli and Klebsiella spp. and P aeruginosa. ESBL and carbapenem.tse prcducers were also detected inE' coli arrd Klebsiella spp. Results of the present study indicate that in Pakistan most of the infections are caused by altibiotic resistarlt bacteda. The identification ofthese bacteria should be done properly. Brilliance ESBL, CRE and MRSA agars were found best for the phenotypic detection of Blactamases, caxbapenemases and MRSA.
dc.identifier.urihttp://repository.uop.edu.pk/123456789/450
dc.language.isoen
dc.publisherCenter of Biotechnology
dc.relation.ispartofseries100011
dc.titleMOLECULAR EPIDEMIOLOGY OF ANTIBIOTIC RESISTANT GENES IN PATHOGENIC BACTERIA, (A CASE STUDY OF KHYBER PUKIITUNKIIWA, PAKISTAI9
dc.typeThesis
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