CHARACTERIZATION OF ANTIBIOTIC PRODUCING SOIL MICROORGANISMS AGAINST HUMAN PATHOGENIC BACTERIA, ISOLATED FROM HOSPITILIZED PATIENTS IN KHYBER PAKHTUNKHWA

Simple item page
dc.contributor.authorRiaz Muhammad
dc.contributor.authorSupervised By: Prof. Dr. Bashir Ahmad
dc.date.accessioned2026-07-16T07:26:17Z
dc.date.available2026-07-16T07:26:17Z
dc.date.issued2013
dc.description.abstractPathogenic bacteria are medically very important as they caused various diseases, develop resistance against antibiotics and that is why require great concern worldwide. Most prominent antibiotic resistant pathogens are Methicillin resistant Staphylococcus aureus (MRSA), Vancomycin intermediate Staphylococcus aureus (VISA), Vancomycin resistant Staphylococcus aureus (VRSA), multi drugs resistant Pseudomonas aeroginosa, extended spectrum beta-lactamases producing Escherichia coli and Enterobacteraciae spp. which cause hospital acquired and community acquired infections. Methicillin and Oxacillin were considered as potent antibiotics against S. aureus infection but unfortunately more than 50% S. aureus resistance to these drugs have been reported from different countries recently. Now Vancomycin is the drug of choice for the treatment of MRSA infection but unfortunately due to the misuse of antibiotics VRSA have been recently evolved. In Khyber Pakhtunkhwa pathogenic bacteria have developed resistance to mostly prescribed antibiotics. According to our survey mostly Oxacillin, Meropenem, Amikacin, Ciprofloaxacin, Ofloaxacin, Piperacillin/Tazobactam and Vancomycin antibiotics are prescribed against bacterial infections in hospitalized patients. Bacterial resistance to these antibiotics has also been reported from different geographical locations of Pakistan. Drug resistance is a serious problem which is often a consequence of the failure of control strategies. In the current scenario our options to deal with the antibiotic resistant bacterial pathogens limited or in-effective. As the resistance evolved comparatively rapidly due to the irrational antibiotic use, therefore we expect a much faster evolutionary rate in a third world country like Pakistan. The problem of resistance could be tackled in several ways including synthetic modification in the existing drugs or looking for novel compounds for neutralizing the threat.
dc.identifier.urihttp://repository.uop.edu.pk/123456789/443
dc.language.isoen
dc.publisherCenter of Biotechnology
dc.relation.ispartofseries100005
dc.titleCHARACTERIZATION OF ANTIBIOTIC PRODUCING SOIL MICROORGANISMS AGAINST HUMAN PATHOGENIC BACTERIA, ISOLATED FROM HOSPITILIZED PATIENTS IN KHYBER PAKHTUNKHWA
dc.typeThesis
Files
Original bundle
Now showing 1 - 2 of 2
No Thumbnail Available
Name:
CHARACTERIZATION OF ANTIBIOTIC PRODUCING SOIL MICROORGANISMS AGAINST HUMAN PATHOGENIC BACTERIA, ISOLATED FROM HOSPITILIZED PATIENTS IN KHYBER PAKHTUNKHWA by Riaz Muhammad.pdf
Size:
1.89 MB
Format:
Adobe Portable Document Format
Download
No Thumbnail Available
Name:
Untitled.jpg
Size:
65.23 KB
Format:
Joint Photographic Experts Group/JPEG File Interchange Format (JFIF)
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed to upon submission
Description:
Download
Collections
PhD Theses and Dissertations