MUHAMMAD AAMIRSupervised By : Dr. Sardar Khan2026-07-282026-07-282015http://repository.uop.edu.pk/123456789/489Globally, hexachlorocyclohexanes (HCHs) and dichlorodiphenyltrichloroethanes (DDTs)are of great concern because of their environmental persistent, long-range transport, bioaccumulative and potentially toxic nature and have been listed as possibly carcinogenic to humans. The purpose of this work was to investigate the occurrence of HCHs and DDTs residues in three different compartments of aquatic ecosystem (sediments, water and fish) and to assess their eco-toxicological and human health risk associated with the consumption of contaminated fish, and to further evaluate the bioaccumulation potential of sediments-associated HCHs and DDTs into the investigated fish.enThesis